Ua holomua mākou i kēia manawa i kahi pūʻulu platelet rich plasma (PRP) a me hyaluronic acid injections no ke kuli OA a he nui ka poʻe i loaʻa i ka maʻi ʻoi aʻe ma mua o ka mea kūpono (ʻo nā mea pane maikaʻi loa ka liʻiliʻi o nā loli radiological), akā ~ 80% ua lōʻihi a ʻoi aku ka maikaʻi o nā pane i ka PRP a i ʻole viscosupplementation ma mua o nā lāʻau corticosteroid intra-articulator ma mua.
ʻO kekahi loiloi hou a me hoʻokahi hoʻokolokolo hou ua hoʻoikaika iaʻu e hana i kēia hōʻano pōkole ma ka PRP a me ka viscosupplementation therapy no nā kuli.
ʻO ka loiloi ma Arthroscopy i hoʻopau i ka PRP "he lapaʻau kūpono no ka OA kuli a hiki ke alakaʻi i ka hōʻailona hōʻailona a hiki i 12 mau mahina".Eia kekahi intra-articular PRP therapy "hāʻawi maikaʻi symptomatic kōkua i nā poʻe maʻi me ka mua o ka kuli degenerative loli, a me kona hoʻohana pono e noʻonoʻo i nā maʻi me ka kuli OA". .
Hoʻolālā hoʻāʻo:
•ʻO ka huina o 162 mau maʻi me nā ʻāpana like ʻole o ke kuli OA i māhele ʻia i ʻehā mau pūʻulu: ua loaʻa i kēlā me kēia me 3 injections i kēlā me kēia: 3 IA doses o PRP, hoʻokahi doses o PRP, 3 inj o HA (hyaluronic acid) a i ʻole he saline injection (control) .
•ʻElua mau pūʻulu: OA mua (Kellgren–Lawrence grade 0 me ka degeneration cartilage a i ʻole ka papa I–III) a me ka OA kiʻekiʻe (Kellgren–Lawrence grade IV).
•Ua loiloi ʻia ka poʻe maʻi ma mua o ka hoʻopaʻa ʻana a ma ka 6 mau mahina e hoʻohana ana i ka EuroQol visual analogue scale (EQ-VAS) a me International Knee Documentation Committee (IKDC).
Nā hualoaʻa:
•Loaʻa ka hoʻomaikaʻi nui ʻana i ka helu IKDC a me ka EQ-VAS ma nā pūʻulu lapaʻau āpau i hoʻohālikelike ʻia me ka pūʻulu mana.
•ʻO ka nui o nā kuli o nā maʻi i mālamaʻia meʻekolu PRP injections iʻoi aku ka maikaʻi ma mua o kēlā mau maʻi o nā hui'ē aʻe.ʻAʻohe ʻokoʻa koʻikoʻi o nā helu o nā maʻi i hoʻopaʻa ʻia me hoʻokahi dosis o PRP a i ʻole HA.
• Ma nā pūʻulu o OA mua, ua loaʻa nā hopena lapaʻau maikaʻi loa i nā poʻe maʻi i mālama ʻia me ʻekolu injections PRP, akā ʻaʻohe ʻokoʻa koʻikoʻi i nā hopena lapaʻau o nā maʻi me ka OA kiʻekiʻe ma waena o nā hui lapaʻau.
Nā hopena:
1.Hōʻike nā hopena lapaʻau o kēia noiʻi intra-articular PRP a me ka mālama HA no nā pae āpau o ke kuli OA.
2.No nā poʻe maʻi me ka OA mua, ʻoi aku ka maikaʻi o nā inikini PRP he nui (3) i ka loaʻa ʻana o nā hopena lapaʻau maikaʻi aʻe.
3.No nā poʻe maʻi me ka OA kiʻekiʻe, ʻaʻole i hoʻomaikaʻi nui ka nui o nā injections i nā hopena o nā maʻi ma kekahi hui.
Ka manawa hoʻouna: Nov-07-2022