ʻO nā lāʻau lapaʻau autologous hou e hoʻohana ana i nā noi platelet-rich plasma (PRP) hiki ke pāʻani i nā hana hoʻohui i nā ʻano hoʻolālā lāʻau lapaʻau regenerative.Loaʻa ka pono ʻole o ka honua no ka hoʻoponopono ʻana i ka ʻiʻo no ka mālama ʻana i ka musculoskeletal (MSK) a me nā maʻi spinal, osteoarthritis (OA), a me nā poʻe maʻi me nā ʻeha paʻakikī a me ka recalcitrant.Hoʻokumu ʻia ka lāʻau lapaʻau PRP ma ka ʻoiaʻiʻo e kākoʻo nā mea ulu platelet (PGFs) i ʻekolu mau manawa o ka hoʻōla ʻana i ka ʻeha a me ka hoʻoponopono ʻana i ka cascade (inflammation, proliferation, remodeling).
Nui nā ʻano hana PRP like ʻole i loiloi ʻia, mai ke kanaka, in vitro, a me nā haʻawina holoholona.Eia nō naʻe, alakaʻi pinepine ʻia nā ʻōlelo aʻoaʻo mai ka in vitro a me ka noiʻi holoholona i nā hopena lapaʻau like ʻole no ka mea paʻakikī ke unuhi ʻana i nā hopena noiʻi non-clinical a me nā ʻōlelo aʻoaʻo i nā kuʻuna lapaʻau kanaka.I nā makahiki i hala iho nei, ua holomua ka hoʻomaopopo ʻana i ka ʻenehana PRP a me nā manaʻo no ka bio formulation, a ua ʻōlelo ʻia nā kuhikuhi noiʻi hou a me nā hōʻailona hou.Ma kēia loiloi, e kūkākūkā mākou i nā hanana hou e pili ana i ka hoʻomākaukau ʻana a me ka haku ʻana o PRP e pili ana i ka hoʻopaʻa ʻana i ka platelet, nā hana leukocyte e pili ana i ka immunomodulation innate a adaptive, nā hopena serotonin (5-HT), a me ka pepehi ʻana i ka ʻeha.Eia kekahi, ke kūkākūkā nei mākou i nā hana PRP e pili ana i ka mumū a me ka angiogenesis i ka hoʻoponopono ʻana i nā kiko a me nā kaʻina hana hou.ʻO ka hope, e nānā mākou i ka hopena o kekahi mau lāʻau lapaʻau i ka hana PRP, a me ka hui pū ʻana o PRP a me nā protocols hoʻoponopono.
PRP Terminology and Classification
ʻO ka hoʻomohala ʻana i nā huahana PRP e hoʻoulu i ka hoʻoponopono ʻana a me ka hana hou ʻana he kahua noiʻi koʻikoʻi i ka ʻepekema biomaterial a me ka lāʻau lapaʻau no nā makahiki he mau makahiki.Hoʻokomo ka tissue healing cascade i nā mea pāʻani he nui, me nā platelets me kā lākou ulu ulu a me nā granules cytokine, leukocytes, fibrin matrix, a me nā cytokines ʻē aʻe he nui, e hana synergistically.I loko o kēia cascade, hiki mai kahi kaʻina coagulation paʻakikī, ʻo ia ka hoʻoulu ʻana o ka platelet a me ka hoʻokuʻu ʻana o nā mea i loko o nā granules dense a me α-platelet, polymerization o fibrinogen (hoʻokuʻu ʻia e nā platelets a manuahi paha i loko o ka plasma) i loko o kahi fibrin mesh, a me ka hoʻomohala ʻana o ka platelet plug. .
Ka manawa hoʻouna: Oct-13-2022