HA PRP Collection Tube

ʻO nā loli pathophysiological koʻikoʻi o ka osteoarthritis kuli ka nalo ʻana o ka cartilage, ka hana hou ʻana o ka iwi subchondral, ka hoʻokumu ʻana o ka osteophyte a me ka hopena inflammatory synovial.ʻO nā hōʻike mua o ka maʻi he pehu, ʻeha a ʻoʻoleʻa o nā hono a me nā ʻiʻo a puni.Me ka holomua ʻana o ka maʻi, alakaʻi mālie ia i ka hui pū ʻana a hoʻopilikia koʻikoʻi i ka maikaʻi o ke ola.Wahi a ka noiʻi, ʻo 2.2% ka nui o ke kino o ka osteoarthritis i ka makahiki 2010, a ʻo ka nui o nā poʻe kīnā i ka makahiki hoʻokahi i ʻoi aku ma mua o 1.7 miliona, i lawe mai i ka pōʻino nui i ke kaiāulu, nā ʻohana a me nā kānaka.He biomaterial polysaccharide mole kiʻekiʻe ʻo HA i hana ʻia e ka hoʻololi pinepine ʻana o ka waikawa n-acetylglucuronic.ʻO ia ka mea nui o ka wai synovial hui a me kekahi o nā ʻāpana o ka cartilage matrix.He kuleana ko ia i ka meaʻai a me ka pale ʻana i nā hono.Ua hōʻoia ʻia ʻo HA i ka mālama ʻana i ka osteoarthritis i kahi hopena i ka hoʻomaha ʻana i nā hōʻailona ʻeha o ke kuli a me ka hoʻomaikaʻi ʻana i ka neʻe ʻana o ke kuli.Eia nō naʻe, ma muli o ka nele o ke kākoʻo e pili ana i nā hōʻike, ʻoi aku ka maopopo ʻole o ka maikaʻi o ka wā lōʻihi, ʻo nā alakaʻi AAOS hou loa no ka hōʻoia a me ka mālama ʻana i ka osteoarthritis ʻaʻole i ʻōlelo ʻia i ka hoʻohana ʻana i ka hyaluronic acid, a ʻoi aku ka ikaika o ka pae ʻōlelo.ʻO Triamcinolone acetonide, ma ke ʻano he glucocorticoid synthetic lōʻihi, he hopena anti-inflammatory ikaika a mau loa.

ʻO kāna hana ke kāohi i ka phagocytosis a me ka hana ʻana o nā antigens e nā macrophages;Hoʻopaʻa i ka membrane lysosomal a hoʻemi i ka hoʻokuʻu ʻana o ka hydrolase i ka lysosome;Kāohi i ka neʻe ʻana o nā leukocytes a me nā macrophages mai nā kīʻaha koko a hoʻemi i ka hopena inflammatory.Ke hōʻike nei kēia haʻawina he maikaʻi ka hopena o ka intra-articular injection o triamcinolone acetonide i loko o hoʻokahi mahina ma hope o ka mālama ʻana, akā me ka manawa o ka hoʻomaha, ʻoi aku ma hope o 6 mau mahina o ka mālama ʻana, ʻoi aku ka haʻahaʻa o ka hopena ma mua o nā hui ʻelua.Ua hōʻike ʻia ʻo Mcalindon a me nā haʻawina ʻē aʻe no nā maʻi maʻi me ka osteoarthritis kuli, intraarticular injection of triamcinolone acetonide i hoʻoemi nui i ka cartilage volume a ʻaʻohe ʻokoʻa koʻikoʻi o ka ʻeha kuli i hoʻohālikelike ʻia me ka saline maʻamau.

ʻAʻole kākoʻo nā haʻawina i luna i kēia lapaʻau no nā maʻi maʻi me ka osteoarthritis kuli.Ua hoʻohana kekahi poʻe noiʻi i ka triamcinolone acetonide a me ka sodium hyaluronate intra-articular injection e mālama i ka osteoarthritis o ke kuli, a ʻoi aku ka maikaʻi o ka wā pōkole a me ka wā lōʻihi ma mua o ka hyaluronic acid wale nō.Ma ke ʻano he lāʻau lapaʻau hou, hiki ke loaʻa iā PRP mai nā maʻi autologous peripheral koko, me ka ʻole o ka pale ʻana, a loaʻa nā kiʻekiʻe o nā kumu ulu.Ua hōʻike ʻia nā mea ulu e hāpai i ka hoʻonui ʻana o ka chondrocyte a me ka hoʻohuihui matrix extracellular.Eia kekahi, ua hōʻike ʻia nā haʻawina hou e hiki i ka PRP ke kāohi i ka maʻi bacterial manuahi o ka synovium i kekahi ʻano ʻoiai e hāpai ana i ka hoʻōla hou ʻana o chondrocyte.ʻOi aku ka nui o nā hoʻokolohua holoholona a me nā noiʻi lāʻau lapaʻau e hōʻike ana i kona pono maikaʻi.Hōʻike kēia haʻawina i ka helu WOMAC o PRP ma 1 a me 3 mau mahina ma hope o ka mālama ʻana ua like ia me ka hyaluronic acid, a ʻo ka WOMAC score o PRP ma 6 mau mahina ma hope o ka mālama ʻana ʻoi aku ka maikaʻi ma mua o nā hui ʻelua ʻē aʻe, e manaʻo ana he loaʻa ia. maikaʻi ma waena a me ka hopena curative lōʻihi.Eia nō naʻe, ma muli o ka loaʻa ʻole o ka hoʻopaʻa ʻana i ka maʻi maʻi lōʻihi o nā laʻana nui a me ka nele o ke kākoʻo pololei mai ka molecular biology a i ʻole MRI imaging, pono mau ka noiʻi a me ke kūkākūkā.